The first human genome map completed in 2001 was based on the improved first-generation sequencing technology (Sanger method). This achievement provides important basic data for understanding the composition, structure, function of the human genome and the mechanism of human disease, and has a profound impact on the fields of medicine and biology. In the field of first-generation sequencing, NAYO’s automated pipetting helps every experimental link.

Whether in PCR amplification, library preparation, gene sequencing or other molecular biology related research, nucleic acid extraction is an indispensable and important step. In the process of nucleic acid extraction, samples usually need to go through operations such as lysis, incubation, centrifugation, and supernatant collection. NAYO fully automatic liquid handling workstation provides accurate and efficient automated solutions for reagent sample addition, mixing, incubation, and supernatant transfer, accelerating the experimental process.

The NAYO series liquid handling workstation is equipped with 96-channel, 8-channel or flexible 1/2-channel pipettes, which are suitable for purification kits of different brands and models as well as user-prepared reagents, and can easily realize reagent packaging and high-throughput sample purification processing. At the same time, the workstation supports the selection of functional modules and the integration of plate stacks, which can realize the automation of the whole process of low, medium and high-throughput sample purification.

PCR molecular detection is one of the main technologies for genetic testing, with advantages such as high sensitivity and strong specificity. In the preparation of the PCR reaction system, factors such as the accuracy and uniformity of the pipetting volume, the presence of bubbles, and the cleanliness of the environment are key factors affecting the test results. In addition, repeated pipetting of large amounts of liquid can easily cause operator fatigue and affect the stability and repeatability of experimental results. Therefore, NAYO automated pipetting workstation directly hits the pain point and launches a full range of solutions for the construction of reaction systems suitable for low, medium, and high sample throughput.

As a key process in genetic testing, library construction requires professionals to perform sample processing and library preparation. As sample throughput increases, manual operation is inefficient and there are risks of operational errors, and personnel need professional training. Manual library preparation has certain limitations. NAYO focuses on the field of NGS automation and has professional, mature, and comprehensive automation solutions for library preparation. NAYO automated library preparation workstation integrates flexible pipetting, temperature control, magnetic separation, oscillation, PCR, quantification and other modules, easily realizing "one-click" fully automatic NGS library preparation.

High-throughput sequencing can perform parallel sequencing of millions to hundreds of millions of DNA molecules at a time, and can provide in-depth, detailed, and comprehensive analysis of a species' transcriptome and genome. With the development of sequencing technology, second-generation sequencing technology has penetrated into all aspects of biological and medical research.

As a key process in genetic testing, library construction requires professionals to perform sample processing and library preparation. As sample throughput increases, manual operation is inefficient and there are risks of operational errors, and personnel need professional training. Manual library preparation has certain limitations. NAYO focuses on the field of NGS automation and has professional, mature, and comprehensive automation solutions for library preparation. NAYO automated library preparation workstation integrates flexible pipetting, temperature control, magnetic separation, oscillation, PCR, quantification and other modules, easily realizing "one-click" fully automatic NGS library preparation.

Source:DNA sequencing from Oxford Nanopore Technologies official website https://www.nanoporetech.net/how_it_works

As the requirements for sequencing quality and sequencing read length become increasingly higher, the third-generation sequencing technology, also known as nanopore single-molecule sequencing, has come into being. The sequencing process does not require PCR amplification, and in theory, it can measure nucleic acid sequences of unlimited length, making it emerging in fields such as genetic testing.